Editorial |
Featured
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News & Views |
Conscripted by collagen
In atherosclerotic plaques, patterns of calcification — which have profound implications for plaque stability and vulnerability to rupture — are determined by the collagen's content and patterning throughout the plaque.
- Jordan D. Miller
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News & Views |
Larger is stealthier
Implanted spheres with a diameter larger than 1.5 mm escape fibrotic responses, thereby extending the survival time of the encapsulated therapeutic cells.
- Ruud A. Bank
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Commentary |
Translating materials design to the clinic
Many materials-based therapeutic systems have reached the clinic or are in clinical trials. Here we describe materials design principles and the construction of delivery vehicles, as well as their adaptation and evaluation for human use.
- Jeffrey A. Hubbell
- & Robert Langer
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Commentary |
Biomaterials in the repair of sports injuries
The optimal stimulation of tissue regeneration in bone, cartilage and spinal cord injuries involves a judicious selection of biomaterials with tailored chemical compositions, micro- and nanostructures, porosities and kinetic release properties for the delivery of relevant biologically active molecules.
- Paul Ducheyne
- , Robert L. Mauck
- & Douglas H. Smith
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Article |
Materials for multifunctional balloon catheters with capabilities in cardiac electrophysiological mapping and ablation therapy
Inflatable balloon catheters are widely used in many surgical and diagnostic procedures. Such catheters have now been used as a platform for a collection of components including semiconductor devices, sensors and actuators, and these multifunctional catheters probed for their use in cardiac-related applications.
- Dae-Hyeong Kim
- , Nanshu Lu
- & John A. Rogers