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Bacteria make protein toxins to compete with other bacteria in microbial communities. A study of a common soil bacterium has revealed a previously unknown type of antibacterial toxin that forms a striking umbrella-like structure.
Oxygen is an essential requirement for aerobic organisms. Here the authors explore the role of oxygen in the antiviral innate response in multiple models of infection and suggest oxygen enhances the antiviral innate response via EGLN1 hydroxylation of IRF3.
Knowledge of pathogenesis mechanisms and effective treatments for viral myocarditis is lacking. Here, Wang et al show that loss of TRIM29 and PERK inhibitor mitigate viral myocarditis by attenuating PERK-driven ER stress and ROS responses in male mice.
A case report of highly pathogenic avian influenza A H5N1 of clade 2.3.4.4b in the brain of a common bottlenose dolphin (Tursiops truncatus) from Florida, United States.
HIV exposed but uninfected infants may face an increased risk of serious infection and mortality. In this work, the authors utilise a cohort from rural Zimbabwe to explore the biological mechanisms underlying infant mortality.
Bacteria make protein toxins to compete with other bacteria in microbial communities. A study of a common soil bacterium has revealed a previously unknown type of antibacterial toxin that forms a striking umbrella-like structure.