Logic gates articles within Nature

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  • News & Views |

    The idea that artificial neural networks could be based on molecular components is not new, but making such a system has been difficult. A network of four artificial neurons made from DNA has now been created. See Letter p.368

    • Anne Condon
  • News & Views |

    Cellular compartmentalization is an effective way to build gene circuits capable of complex logic operations, in which binary inputs are converted into binary outputs according to user-defined rules. See Letters p.207 & p.212

    • Bochong Li
    •  & Lingchong You
  • News & Views |

    Computers use transistor-based logic gates as the basis of their functions, but molecular logic gates would make them much faster. A report of DNA-based logic gates could be a first step towards molecular computing.

    • Thomas Carell
  • Letter |

    For synthetic biologists' creativity to be unleashed, basic circuits must become truly interchangeable, that is, modular and scalable. This study, one of two linked papers, has harnessed bacterial 'quorum sensing' to achieve complex computation through communication between individual cells performing simple logic functions. Such extracellular 'chemical wiring' is one promising way to get around intracellular noise when building more complex genetic circuitry.

    • Alvin Tamsir
    • , Jeffrey J. Tabor
    •  & Christopher A. Voigt