Abstract
PREVIOUS attempts, using infantile mice or rats as test animals, to demonstrate the presence of a gonadotropic substance in the anterior pituitary of frogs have been entirely negative1. Since implantation of frog's pituitary into frogs causes ovulation, Zondek comes to the conclusion that the frog's pituitary contains a gonadotropic substance which is inactive in warm-blooded animals. The negative results obtained by Lipschutz and Paez and Zondek were probably due to the fact that the amount of pituitary tissue implanted was too small. Adams and Tukey, however, injected saline suspensions of from 16 to 96 frogs' pituitaries into each infantile mouse and still obtained negative results.
Similar content being viewed by others
Article PDF
References
Lipschutz, A., and Paez, R., Compt. rend. Soc. biol., 99, 693 (1928). Zondek, B., Arch. Gynäk., 144, 133 (1930). Adams, A. E., and Tukey, G. R., Anat. Rec., 67, Supp. 2 (1937).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
ZWARENSTEIN, H. Gonadotropic Activity of Amphibian Anterior Pituitary. Nature 140, 588 (1937). https://doi.org/10.1038/140588b0
Published:
Issue Date:
DOI: https://doi.org/10.1038/140588b0
This article is cited by
-
Photodynamic Action of Carcinogenic Agents
Nature (1937)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.