Abstract
As has been shown by Kahlson et al., in rats fed on a histamine-free diet, the urinary excretion of histamine begins at about the fifteenth day of pregnancy and increases rapidly. The peak value occurs 1 or 2 days before birth, then falls steeply to the pre-pregnant level. The increase in histamine excretion depends on the number of young in the litter; the larger the number, the greater the increase in histamine excretion1.
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References
Kahlson, G., Rosengren, Elsa, and Westling, H., J. Physiol., 143, 91 (1958).
McIntire, Floyd C., Roth, L. W., and Shaw, J. L., J. Biol. Chem., 170, 537 (1947).
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WISKONT-BUCZKOWSKA, H. Relationship between the Decrease in Urinary Excretion of Histamine and the Initiation of the Labour Process. Nature 191, 290 (1961). https://doi.org/10.1038/191290a0
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DOI: https://doi.org/10.1038/191290a0
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