Abstract
DURING work on drug antagonism, it was found incidentally that isolated small intestines of guinea pigs contracted reversibly with picric acid, and the mode of this action was examined in detail, using the organ bath of 30 ml. at the bath temperature of 26° C., on isolated small intestines of guinea pigs1. All the results given here are the mean of at least ten experiments.
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References
Takagi, K., and Kimura, M., Pharm. Bull., 5, 440 (1957). Takagi, K., and Takayanagi, I., ibid., 5, 580 (1957).
Takayanagi, I., Chem. Pharm. Bull., 9, 187 (1961).
Schaumann, W., Brit. J. Pharmacol., 10, 456 (1955).
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TAKAGI, K., TAKAYANAGI, I. Liberation of Acetylcholine from the Small Intestines of Guinea Pigs and Cats after Treatment with Picric Acid. Nature 193, 589–590 (1962). https://doi.org/10.1038/193589a0
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DOI: https://doi.org/10.1038/193589a0
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