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Increase of the Effect of Histamine by E. coli Endotoxin on the Smooth Muscle

Abstract

ONE of the properties of the Brucella abortus and B. melitensis endotoxins is their ability to promote motility of the uterus muscle—this we demonstrated recently1,2. The Brucella endotoxins can induce a remarkable sensitivity in the isolated uterus against oxytocin1–4 and histamine3,5 which cannot be observed in the ileum5.

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References

  1. Urbaschek, B., Zbl. Veterinärmed., 8, 150 (1961).

    CAS  Google Scholar 

  2. Urbaschek, B., Nature, 202, 883 (1964).

    Article  ADS  CAS  Google Scholar 

  3. Urbaschek, B., Kotowski, H., and Bäurle, H., Z. ImmunForsch., 122, 343 (1961).

    Google Scholar 

  4. Urbaschek, B., Vortr. Med. Forschungsanstalt Max-Planck-Ges., Göttingen (Dec. 11, 1963).

  5. Urbaschek, B., Schmutzler, W., Versteyl, R., and Giertz, H., (to be published).

  6. Boivin, A., Mesrobeanu, J., and Mesrobeanu, L., C.R. Soc. Biol., Paris, 114, 307 (1933).

    CAS  Google Scholar 

  7. Boivin, A., and Mesrobeanu, L., C.R. Soc. Biol., Paris, 115, 304 (1934).

    CAS  Google Scholar 

  8. Boivin, A., and Mesrobeanu, L., Rev. Immunol., 3, 319 (1937).

    Google Scholar 

  9. Urbaschek, B., Z. ImmunForsch., 120, 279 (1960).

    CAS  Google Scholar 

  10. Wiedermann, J., Stone, M. L., and Pataki, R., Amer. J. Obstet. Gynec., 84, 290 (1962).

    Article  Google Scholar 

  11. Goodno, J. A., and Kumar, D., Amer. J. Obstet. Gynec., 85, 698 (1963).

    Article  Google Scholar 

  12. Thomas, L., Ann. Rev. Physiol., 16, 467 (1954).

    Article  CAS  Google Scholar 

  13. Thomas, L., Immunpathol. First Intern. Symp., Basle/Seelisberg 1958, 325. (Benno Schwabe and Co., Basle-Stuttgart, 1959).

    Google Scholar 

  14. Kass, E. H., Trans. Assoc. Amer. Physicians, 69, 56 (1956).

    CAS  Google Scholar 

  15. Kass, E. H., Trans. Assoc. Amer. Physicians, 72, 257 (1959).

    Google Scholar 

  16. Douglas, W. W., J. Physiol. (Lond.), 126, 319 (1957).

    Article  Google Scholar 

  17. Gilbert, R. P., Physiol. Rev., 40, 245 (1960).

    Article  MathSciNet  CAS  Google Scholar 

  18. Hinshaw, L. B., Vick, J. A., Jordan, M. M., and Wittmers, L. E., Amer. J. Physiol., 202, 103 (1962).

    CAS  PubMed  Google Scholar 

  19. Spink, W. W., in Bock, K. D., Intern. Symp. Basle, 251 (Springer-Verlag, Berlin-Göttingen-Heidelberg, 1962).

    Google Scholar 

  20. Vick, J., J. Lab. Clin. Med., 56, 953 (1960).

    Google Scholar 

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URBASCHEK, B., VERSTEYL, R. Increase of the Effect of Histamine by E. coli Endotoxin on the Smooth Muscle. Nature 207, 763–764 (1965). https://doi.org/10.1038/207763a0

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