Abstract
INCREASING the amount of urea in the plasma has been shown to enhance urine concentration in many mammals (man, cat, dog, sheep, white rat, kangaroo rat, jerboa1,2, and rabbit3). In some mammals, however, changing the concentration of urea does not affect urine concentration; in the pig, beaver and Aplodontia, enhancement does not occur1,3. It was hypothesized that the inability of the latter group to raise its urine osmotic ceiling following increases in plasma urea is a primitive condition because these species are relatively primitive, phylogenetically.
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References
Schmidt-Nielsen, B., O'Dell, R., and Osaki, H., Amer. J. Physiol., 200, 1125 (1961).
Schmidt-Nielsen, B., and O'Dell, R., Amer. J. Physiol., 197, 856 (1959).
House, E. W., Pfeiffer, E. W., and Braun, H. A., Nature, 199, 181 (1963).
Reynolds, H. C., Sci. Amer., 188, 88 (1953).
Dolph, C. I., Braun, H. A., and Pfeiffer, E. W., Physiol. Zool., 35, 263 (1962).
Richter, H. J., and Lapointe, Y. S., Clin. Chem., 5, 617 (1959).
Sperber, I., Zoologiska Bidrag fran Uppsala, 22, 249 (1944).
Plakke, R. K., and Pfeiffer, E. W., Science, 146, 1683 (1964).
Moffat, D. B., and Fourman, J., J. Anat., 97, 543 (1963).
Fourman, J., and Moffat, D. B., Symp. Zool. Soc. Lond., No. 11, 57 (1964).
Pfeiffer, E. W., Nungesser, W. C., Iverson, D. A., and Wallerius, J. F., Anat. Rec., 137, 227 (1960).
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PLAKKE, R., PFEIFFER, E. Influence of Plasma Urea on Urine Concentration in the Opossum (Didelphis marsupialis virginiana). Nature 207, 866–867 (1965). https://doi.org/10.1038/207866a0
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DOI: https://doi.org/10.1038/207866a0
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