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Chemical Components in the Cell Wall of Salmonella typhimurium affecting its Virulence and Immunogenicity in Mice

Nature volume 222, pages 1085–1086 (1969)Cite this article

Abstract

THE cell wall is the first structure of most bacteria to interact with the host, so its chemical constitution may be important in the relationship between parasite and host. Studies of cell wall lipopolysaccharide (LPS) biosynthesis in Salmonella typhimurium have led to the isolation of a number of mutants which are defective in enzymes catalysing different synthetic steps1,2. We have examined the virulence and immunogenicity of such mutants.

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Authors and Affiliations

  1. Department of Microbiology, Keio University School of Medicine, Shinano-machi, Tokyo

    MASAYASU NAKANO & KAZUHISA SAITO

Authors
  1. MASAYASU NAKANO
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  2. KAZUHISA SAITO
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NAKANO, M., SAITO, K. Chemical Components in the Cell Wall of Salmonella typhimurium affecting its Virulence and Immunogenicity in Mice. Nature 222, 1085–1086 (1969). https://doi.org/10.1038/2221085a0

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