Abstract
THE adenoviruses comprise a group of icosahedral animal viruses1,2 with two types of capsid proteins. One of these, called the penton, occupies the five-fold positions at the twelve corners of the icosahedron. The other, called the hexon, occupies the six-fold positions on the faces and edges of the icosahedron, there being 240 hexons on the surface of each virus particle. The hexon antigen contains both group specificity, demonstrated by complement fixation and gel diffusion, and type specificity demonstrated by its ability to induce type-specific neutralizing antibody3.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Pereira, H. G., and Valentine, R. C., Brit. Med. Bull., 23, 129 (1967).
Valentine, R. C., and Pereira, H. G., J. Mol. Biol., 13, 13 (1965).
Kjellen, L., and Pereira, H. G., J. Gen. Virol., 2, 177 (1968).
Pereira, H. G., Valentine, R. C., and Russell, W. C., Nature, 219, 946 (1968).
Köhler, K., Z. Naturf., 206, 747 (1965).
Pettersson, V., Philipson, L., and Höglund, S., Virology, 33, 575 (1967).
Terry, W. D., Matthews, B. W., and Davies, D. R., Nature, 220, 239 (1968).
Avey, H. P., Poljak, R. J., Rossi, G., and Nisonoff, A., Nature, 220, 1249 (1968).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MACINTYRE, W., PEREIRA, H. & RUSSELL, W. Crystallographic Data for the Hexon of Adenovirus Type 5. Nature 222, 1165–1166 (1969). https://doi.org/10.1038/2221165a0
Received:
Issue Date:
DOI: https://doi.org/10.1038/2221165a0
This article is cited by
-
Comparative studies of adenovirus hexon antigens
Archiv f�r die gesamte Virusforschung (1972)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.