Abstract
SPONTANEOUS tumours in Nicotiana were first reported by Kostoff1 and are called genetic tumours2. They arise on certain interspecific tobacco hybrids2, and it has been proposed that certain genes when appropriately combined in a hybrid promote the development of tumours3,4. Though in bacterially induced crown gall tumours the tumour state is transmissible from a tumour cell to a normal cell in the absence of viable bacteria5,6, efforts to demonstrate an ability of genetic tumours to induce tumour development across a graft union have failed2. Attempts to graft Nicotiana glauca×Nicotiana langsdorffi hybrid tumour tissues from sterile culture to non-parental species of Nicotiana were unsuccessful because the grafts died7,8. Here we report the successful grafting of N. glauca×N. langsdorffii amphidiploid (GGLL) tissue from sterile culture on to N. tabacum cv. Wisconsin 38. Within a month of grafting, the graft (GGLL tumour tissue) induced the development of host (N. tabacum) shoots in wound sites and some grafts became chimaeral.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Kostoff, D., Zbl. Bakt. Parasitk de, II abt., 81, 244–260 (1930).
Smith, H. H., Progr. exp. Tumour Res., 15, 138–164 (1972).
Ahuja, M. R., Molec. gen. Gent., 103, 176–184 (1968).
Näf, U., Growth, 22, 167–180 (1958).
Aaron-Da Cunha, M. I., C. r. hebd. Séanc. Acad. Sci., Paris, 268, 318–321 (1969).
Meins, Jr., F., Differentiation, 1, 21–25 (1973).
White, P. R., Cancer Res., 4, 791–794 (1944).
White, P. R., and Braun, A. C., Cancer Res., 2, 597–617 (1942).
Sussex, I. M., Clutter, M. E., and Goldsmith, M. H. M., Am. J. Bot., 59, 797–804 (1972).
Schaeffer, G. W., and Smith, H. H., Pl. Physiol., 38, 291–297 (1963).
Braun, A. G. (ed.), Progr. exp. Tumour Res. 15 (1972).
Schaeffer, G. W., Nature, 196, 1326–1327 (1962).
Chilton, M., et al., Proc. natn. Acad. Sci. U.S.A., 71, 3672–3676 (1974).
Drlica, K. A., and Kado, C. I., Proc. natn. Acad. Sci, U.S.A., 71, 3677–3681 (1974).
Linsmaier, E. M., and Skoog, F., Physiol. Pl., 18, 100–127 (1965).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
MCDANIEL, C., SUSSEX, I. Host growth induced by genetic tumour grafts. Nature 256, 319–320 (1975). https://doi.org/10.1038/256319a0
Received:
Accepted:
Issue Date:
DOI: https://doi.org/10.1038/256319a0
This article is cited by
-
Somatic hybrids of plants by fusion of protoplasts
MGG Molecular & General Genetics (1978)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.