Abstract
THE mechanism by which molecules interact with, and so stimulate, the surfaces of olfactory receptor cells has given rise to much speculation. Since oil-soluble substances are often very effective odours, it has been proposed that olfactory transduction occurs when an odorant molecule perturbs the lipids of the sensory membranes. Conversely, the known steric aspects of odorant molecule interactions argue for a more specific binding for which a protein would be a more suitable receptor1–4.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 51 print issues and online access
$199.00 per year
only $3.90 per issue
Buy this article
- Purchase on Springer Link
- Instant access to full article PDF
Prices may be subject to local taxes which are calculated during checkout
Similar content being viewed by others
References
Davies, J. T., in Handbook of Sensory Physiology, 4 (edit. by Beidler, L. M.), part 1, 322 (Springer, New York, 1971).
Amoore, J. E., in Taste and Smell in Vertebrates (CJBA Foundation Symposium) (edit. by Wostenholme, G. E, W., and Knight, J.), 293 (Churchill, London, 1970).
Mazziotti, A., Nature, 250, 645 (1974).
Wright, R. H., Nature, 209, 571 (1966).
McConnell, H. M., and McFarland, B. G., Q. Rev. Biophys., 3, 91 (1970).
Roubal, W. T., Prog. Chem. Fats, 13, 63 (1972).
Moulton, D. G., Celebi, G., and Fink, R. P., in Taste and Smell in Vertebrates (CIBA Foundation Symposium), (edit. by Wolstenholme, G. E. W., and Knight, J.), 227–250 (Churchill, London, 1970).
Getchell, M. L., Gesteland, R. C., Proc. natn. Acad. Sci. U.S.A., 69, 1494 (1972).
Getchell, T. U., Getchell, M. L., Ann. N. Y. Acad. Sci., 237, 62 (1974).
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
BANNISTER, L., CLARK, A., DUNNE, L. et al. Electron spin resonance measurements of molecular interactions in mouse olfactory epithelium. Nature 256, 517–518 (1975). https://doi.org/10.1038/256517a0
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1038/256517a0
This article is cited by
-
The central tubuli in distal segments of olfactory cilia lack dynein arms
Experientia (1976)
Comments
By submitting a comment you agree to abide by our Terms and Community Guidelines. If you find something abusive or that does not comply with our terms or guidelines please flag it as inappropriate.