Abstract
THE functional properties of neurones which contain biogenic amines are usually proposed from the results of studies involving ablation or pharmacological intervention1. Monoamine(MA) neurones are seldom identifiable in vivo, which impedes direct investigations of their functions. The central nervous ganglia of leeches are comprised of about 350 neurones, nine of which contain amines as their putative neurotransmitters. These MA neurones are vitally and selectively stained by Neutral Red dye2, a procedure potentially facilitating intracellular studies of this population of biochemically related cells. We report here the electrophysiological properties of the red-staining neurones within the central nervous system (CNS) of the leech.
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References
Heller, A. in The Nervous System 1, 409–418 (Raven, New York, 1976).
Stuart, A. E., Hudspeth, A. J. & Hall, Z. W. Cell. Tiss. Res. 55–61 (1974).
Nicholls, J. G. & Baylor, D. A. J. Neurophysiol. 16, 740–756 (1968).
Marsden, C. A. & Kerkut, G. A. Comp. Biochem. Physiol. 31, 851–862 (1969).
Rude, S. J. comp. Neurol. 136, 349–372 (1969).
Rude, S., Coggeshall, R. E. & Van Orden, L. S. J. Cell Biol. 41, 832–854 (1969).
Ehinger, B., Falck, B. & Myhrberg, H. E. Histochemie 15, 140–149 (1968).
Kristan, W. B., Jr in The Neurosciences: A Third Study Program 371–377 (MIT Press, Cambridge, Mass. 1974).
Stuart, A. E. J. Physiol., Lond. 209, 627–646 (1970).
Walker, R. J. in Neurobiology of Invertebrates 227–253 (Plenum, New York, 1967).
Getting, P. A. & Willows, A. O. D. J. Neurophysiol. 37, 858–868 (1974).
Lent, C. M. Science 179, 693–696 (1973).
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LENT, C., FRAZER, B. Connectivity of the monoamine-containing neurones in central nervous system of leech. Nature 266, 844–847 (1977). https://doi.org/10.1038/266844a0
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DOI: https://doi.org/10.1038/266844a0
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