Channels that conduct anions or cations across cell membranes are of immense physiological importance. But what do they look like? A chloride channel turns out to have a double-barrelled structure quite unlike that of cation channels.
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Gadsby, D. Two-bit anion channel really shapes up. Nature 383, 295–296 (1996). https://doi.org/10.1038/383295a0
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DOI: https://doi.org/10.1038/383295a0