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Cdk5 checks p27kip1 in neuronal migration

p27kip1, once confined to control of the cell cycle, has more recently been identified as a key regulator of cell migration. In neuronal cells, this function of p27kip1 is regulated by Cdk5.

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Figure 1: The roles of p27kip1 in neurons.

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Reiner, O., Sapir, T. Cdk5 checks p27kip1 in neuronal migration. Nat Cell Biol 8, 11–13 (2006). https://doi.org/10.1038/ncb0106-11

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