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Might makes right: Using force to align the mitotic spindle

Both symmetric and asymmetric divisions rely on alignment of the mitotic spindle with cues from the environment. A study now shows that mitotic spindles find their position by reading the map of forces that load-bearing retraction fibres exert on the cell body.

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Figure 1: How do retraction fibres align the mitotic spindle?
Figure 2: Using force to align the mitotic spindle.

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Correspondence to Buzz Baum.

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Lancaster, O., Baum, B. Might makes right: Using force to align the mitotic spindle. Nat Cell Biol 13, 736–738 (2011). https://doi.org/10.1038/ncb0711-736

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