Post-translational modifications (PTMs) are ubiquitous in all forms of life and often modulate critical protein functions. Recent chemical and biological advances have finally enabled scientists to precisely modify proteins at physiologically relevant positions, ushering in a new era of protein studies.
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Acknowledgements
K.W.B. acknowledges support from the NSF (DGE-1122492), and J.R. is supported by the NIH (R01GM125951; R01GM117230; P01DK017433; U54CA209992).
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Barber, K., Rinehart, J. The ABCs of PTMs. Nat Chem Biol 14, 188–192 (2018). https://doi.org/10.1038/nchembio.2572
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DOI: https://doi.org/10.1038/nchembio.2572
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