Sugar binding by a variety of biomolecules is generally assumed to rely on hydrogen bonding and ionic interactions. A new study shows that arene-carbohydrate interactions are enthalpically driven through nontraditional C-H···π type hydrogen bonds.
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Katie Ris-Vicari
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Tatko, C. Sugars stack up. Nat Chem Biol 4, 586–587 (2008). https://doi.org/10.1038/nchembio1008-586
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DOI: https://doi.org/10.1038/nchembio1008-586
