Uncovering how the immune system of the mucosa surmounts allergic reactions may open new avenues to treat inflammatory conditions in the gut. New findings in mice now show that a C-type lectin receptor in dendritic cells (DCs) protects against food antigens that cause systemic anaphylaxis—promoting oral tolerance (pages 1128–1133).
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Rabinovich, G. A sweet path toward tolerance in the gut. Nat Med 16, 1076–1077 (2010). https://doi.org/10.1038/nm1010-1076
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DOI: https://doi.org/10.1038/nm1010-1076
