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RNA FOLDING

Tracking RNA structures as RNAs transit through the cell

Nature Structural & Molecular Biology volume 26, pages 256–257 (2019)Cite this article

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RNAs perform diverse cellular functions that are mediated at least in part by their structure. However, how RNA structure changes throughout the RNA lifecycle and how these changes affect RNA function remain incompletely understood. A detailed in vivo characterization of RNA structure in various cellular subcompartments now provides insights into how RNA structural changes influence translation, RNA decay, protein binding and RNA modification.

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Fig. 1: RNA structures throughout cellular subcompartments.

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Author information

Authors and Affiliations

  1. Tri-Institutional Training Program in Computational Biology and Medicine, Weill Cornell Medicine, New York, NY, USA

    Angela M Yu

  2. Department of Chemical and Biological Engineering, Northwestern University, Evanston, IL, USA

    Angela M Yu & Julius B. Lucks

  3. Center for Synthetic Biology, Northwestern University, Evanston, IL, USA

    Julius B. Lucks

Authors
  1. Angela M Yu
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  2. Julius B. Lucks
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Correspondence to Julius B. Lucks.

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The authors declare no competing interests.

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Yu, A.M., Lucks, J.B. Tracking RNA structures as RNAs transit through the cell. Nat Struct Mol Biol 26, 256–257 (2019). https://doi.org/10.1038/s41594-019-0213-2

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