Editorials

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  • The first membrane protein structure was reported almost 40 years ago. In this issue, we are publishing a set of papers that serve to underline the incredible advances in our understanding of the biology of these multifaceted molecular machines.

    Editorial
  • In addition to the usual dose of compelling science, our March issue features thoughtful reflections on the last 30 years from readers, as well as past and present editors. Perhaps influenced by these pieces or by our stunning cover — or maybe it is just the changing seasons — we are in an introspective mood this month.

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  • First discovered more than five decades ago, protein ubiquitylation has proven to be an omnipresent post-translational modification regulating virtually every eukaryotic cellular process. With novel clinical applications and recent studies demonstrating ubiquitylation of biomolecules other than proteins, the interest in ubiquitin will not waver any time soon.

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  • As 2023 comes to an end, we take this opportunity to look back through the pages of Nature Structural & Molecular Biology and consider some of the year’s highlights.

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  • In January 2024, Nature Structural & Molecular Biology (NSMB) will celebrate the 30th anniversary of publishing its first issue. Though initially launched as Nature Structural Biology in 1994, the journal has since expanded its scope to include all research into the molecular underpinnings of life, with the vision that the broadest insight can be gleaned through a suite of complementary approaches.

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  • Understanding the underlying molecular mechanisms of dosage compensation and how cells equalize gene expression from the sex chromosomes has interested scientists for more than six decades. However, with so many questions still unanswered, the field continues to capture the attention of researchers.

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  • As 2021 comes to an end, we take this opportunity to look back through the pages of Nature Structural & Molecular Biology and consider some of the year’s highlights.

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  • In the last year and a half, our lives have changed dramatically. Nature Structural & Molecular Biology has also changed. Here we share some of the positive changes that we are embracing.

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  • We celebrate the 50th anniversary of the Protein Data Bank together with our colleagues at Nature Methods with a special collection that showcases key achievements in structural biology and views of its future.

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  • Rapid progress is being made in our understanding of RNA–protein interactions, their role in disease and their influence on the action of oligonucleotide drugs.

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  • Initiatives to promote transparency in our peer-review process and reproducibility start to take off.

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  • Chromatin-associated proteins are emerging as new drug targets for a variety of diseases, especially cancer. This special Focus issue highlights various approaches for ‘targeting chromatin’ for therapeutic intervention.

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  • On 15 July 2019, the Governor of the Bank of England announced that English mathematician, computer scientist and cryptanalyst Alan Turing will be the new face of the £50 note.

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  • We launch a Series on Synaptic Processes, featuring commissioned Reviews and opinion pieces that discuss the expanding molecular understanding of how neural cells communicate.

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  • This January 2018 issue starts the 25th year of NSMB’s journey. We mark the occasion by launching a special series that celebrates the exciting research uncovering the fundamental principles behind biological processes.

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  • Nature research journals announce new reporting summaries to promote transparency, and our editors welcome early-career researchers to the Springer Nature office in New York to discuss careers in scientific publishing.

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